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Chloraprep -
For Preventing Infection
One complication associated
with the insertion of peripherally inserted central
catheters is infection. We all have bacterial organisms
on our skin. If proper antiseptic technique is not followed,
the bacteria may colonize the catheters and migrate
into the blood stream causing serious infections which
may even turn fatal. Proper antiseptic measures must
be taken to prevent this during PICC insertion.
Antiseptic solutions
used during insertion greatly reduce the risk of infection
when properly used. One such solution, now considered
the best for preventing infections during the insertion
and maintenance of a PICC line, is Chloraprep. Chloraprep
is a new skin disinfectant which contains 2% chlorhexidine
gluconate in 70% isopropyl alcohol. It is a recently
approved antiseptic, replacing isolated chlorhexidine
and recommended by the CDC, for preoperative and preprocedural
skin preparation.
Various studies have
shown that infection can occur with bacteria like Staphylococcus
and Klebsiella. Chloraprep effectively eliminates these
bacteria from the catheter entry site thereby preventing
infection. Moreover Chloraprep does not cause skin irritation
unlike many other antiseptics used for this purpose.
It has enhanced antiseptic action against various bacteria,
especially against Staphylococcus epidermidis, a common
bacteria causing infection in venous access devices,
when compared to other antiseptics such an undiluted
chlorhexidine or betadine.
In fact, betadine, or
povidone iodine, was long considered one of the best
known and effective skin disinfectants because it eliminates
most of the skins' bacteria. Chloraprep, however, is
considered better and studies have proved that it is
more efficacious. In one study done by Harvard Medical
School concerning neonates with peripheral catheters,
the bacterial colonization of the catheter was 9.3%
when betadine was used and was reduced to 4.7% when
Chloraprep was the antiseptic. Entry of bacteria in
to the blood stream occurred only in 0.2% of the patients
when both products were used.
However, fighting infection
does not end after the PICC line is inserted. A nonabsorbent
anchoring device secures the catheter and a small foam
disc, called a Biopatch, which is impregnated with chlorhexidine
gluconate, can be placed directly at the insertion site.
This round patch, which has a slit to assist with its
application and removal, fits around the catheter at
the site. This patch provides antimicrobial action for
up to seven days. A sterile transparent dressing then
covers the site.
Proper sterile technique
is very important for preventing various catheter related
infections and Chloraprep is the current and recently
recommended antiseptic of choice to assist in the endeavor.
With careful assessment, scheduled dressing changes
including the anchoring device and Biopatch, and aspectic
expertise, a infection becomes a low risk in a PICC
line.
The consumer health information
on this Website is for informational and educational
purposes only and is not a substitute for medical advice
or treatment for any medical conditions.
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